Lymphotoxin alpha regulates the immunosuppressive functions of

The present invention relates to regulatory T cell and uses thereof. By their immunosuppressive and anti-inflammatory activities, regulatory T cells […]

Rankl to boost thymic regeneration

Cytoablative treatments lead to severe damages on thymic epithelial cells (TECs), which result in delayed de novo thymopoïesis and a prolonged period […]

Sphingosine kinase 1 a new tumor target for enhancing the potency of

The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates […]

Chimeric receptor for use in whole-cell sensors for detecting analytes

The present invention relates to chimeric receptors that can be used in whole-cell sensors for detecting analytes of interest. The inventors showed […]

New biomarker for stratifying cancer patients for immune checkpoint

The present invention relates to use of soluble CD27 as a biomarker to predict the reponse to an immune checkpoint inhibitor treatment. Inventors have […]

New method using imaging analysis for assisting with prognosis of

The present invention relates to a method for assisting with lymphoma prognosis. The prognosis of therapeutic response of patients with lymphoma is […]

Use of cd9 as a biomarker and as a biotarget in glomerulonephritis

The mechanisms driving the development of extracapillary lesions in focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) […]

Antibody for the treatment of myocardial infarction

The present invention relates to a method for treating MI or AMI in a subject in need thereof comprising a step of administering to said subject a […]

Rock inhibitors to treat diabetic retinopathy

In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. […]

Method to restore or improve cognitive functions

The present invention relates to the field of memory and cognitive functions. Here the inventors show that memory stimulations induce autophagy in the […]