Methods and compositions for promoting wound healing in a subject

The present invention relates to a method for promoting wound healing in a subject suffering from Ectodermal dysplasia in need thereof comprising a […]

Use of jak inhibitors for the treatment of painful conditions

An increasing body of evidence suggests that Nav1.7 encoded by SCN9A gene may play a key role in various pain states, including acute, inflammatory […]

Selective pharmacological inhibition of epac1 for the treatment of

The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no cure for IPF. The inventors showed that EPAC1 […]

Methods and compositions for treating cell senescence accumulation

The inventors have surprisingly demonstrated that GD3 positive senescent cells inhibit NK cell in vitro and in vivo while GD3 negative senescent cells […]

Method for early prediction of neurodegenerative decline

The present invention relates to a method for predicting risks of neurodegenerative decline of a patient, especially of mild cognitive impairment […]

Use of shp2 inhibitors for the treatment of insulin resistance

Despite reaching an epidemic status worldwide, metabolic disorders, notably diabetes, still miss efficient and specific therapeutic strategies because […]

Methods and pharmaceutical compositions for the treatment of chronic

The present invention relates to methods and pharmaceutical compositions for the treatment of chronic kidney disease. The inventors used the CMap […]

Hla-class ii artificial antigen presenting cells in cd4 + t cell-based

CD4 T cell help is essential to promote robust cytotoxic T cell responses and could be harnessed to improve outcomes of cancer immunotherapy. To […]

Combination of arsenic and interferon alpha for the treatment of

The present invention relates to methods and pharmaceutical compositions for the treatment of myeloproliferative disorders in patients presenting a […]

Retinoic acid and arsenic trioxide trigger degradation of mutated

The present invention relates to methods and pharmaceutical compositions for the treatment of acute myeloid leukemia. In particular, the present […]