Methods and pharmaceutical composition for treating ciliopathies

Inventors have found that CB1 inhibition (genetic invalidation or using a pharmacological peripheral blockade) reduces CKD and fibrosis in the severe […]

Use of inhibitors of the hippo signalling pathway for the treatment of

Chronic nephropathies represent a real global public health concern. In particular, nephronophthisis (NPH) is an orphan genetic disease affecting the […]

Methods and pharmaceutical compositions for the treatment of autosomal

Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease affecting 1 in 1,000 to 1 in 2,500 individuals worldwide. The […]