Familial adenomatous polyposis (FAP) patients harbor mutations in the APC gene and will develop adenoma and early colorectal cancer. Taking biopsies […]

Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer patients by unleashing exhausted CD8+ T-cell […]

The present invention relates to a treatment of Th cell-associated disorders. Here, theinventors The inventors show that Treg-dependent suppressive […]

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in need thereof comprising administering to the […]

This murine cell line is the first syngenic hormone receptor-positive cell line of C57BL/6 strain. The cell line can be transplanted to C57BL/6 female […]

The present invention relates to an antibody, which is capable of binding to theNeuromedin N long fragment, and Neurotensin long fragment with high […]

We have developed a MCF7-derived cell line stably co-expressing the pleckstrin homology (PH) domain of Akt fused to Renilla luciferase (Luc-Akt-PH) […]

Lung fibroblast play an important role in lung cancer tumor microenvironment (TME). Senescence is involved in the pathophysiology of tumorogenesis. […]

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of CD1a by Sézary cells. CD1a therefore […]

The present invention relates the stratification and treatment of patient suffering from a cancer. In this study, the inventors analyzed the adenosine […]