Immune checkpoint blockade therapy is based on the inhibition of the tumor-mediated suppression of anticancer immune responses. However, the efficacy […]
The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates […]
The present invention relates to a method and composition for treating melanoma. More particularly, inventors have shown that high expression of USP14 […]
Immune checkpoint inhibitors (ICI) have revolutionized therapy for advanced cancer, however many patients still do not respond to treatment. However, […]
The present invention relates to a method and composition for treating melanoma, aggressive/invasive melanoma, metastatic melanoma or melanoma […]
The present invention relates to a method for treating a subject suffering from melanoma resistant by administering to said subject an inhibitor of […]
The response of subjects suffering from cancer to MAPK inhibitors is dramatically impaired by secondary resistances and rapid relapse. So far, the […]