Cd8 t cells modified to express mutated cxcr4 or partially deleted and

The present invention relates to modified T cells, and in particular to CD8 T cells, for use in therapy. The current inventors investigates the effect […]

CHIM21325-T1

New anti-infective compounds

The present invention concerns new tricyclic spirolactams (TriSLas) compounds and their use as a drug, in particular for the prevention and/or […]

Indole-3-propionic acid as an important contributor to viral infection

The gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, the inventors used […]

A composition comprising lipid nanoparticles and an antifungal polyene

The present invention relates to a composition comprising an aqueous phase, a polyene antifungal and lipid nanoparticles which are dispersed in the […]

Methods and pharmaceutical compositions for the treatment of bacterial

The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial superinfections post-influenza. In particular, […]

Methods and pharmaceutical compositions for the treatment of bacterial

The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present […]

Antisense oligonucleotides and ceftriaxone in the strategy against

The present invention relates to the treatment of infections due to antibiotic-resistant bacteria. Antimicrobial resistance (AMR) has been observed at […]

Use of drugs that stiffen mature gametocytes for blocking transmission

The spleen clears rigid erythrocytes from the circulation. Drug-induced stiffening of Plasmodium falciparum intra-erythrocytic sexual stages (mature […]

New 6-6 or 5-6 fused bicyclic compounds comprisingpyrimidine useful in

The present invention relates to new specific 6-6 or 5-6 fused bicyclic compounds comprising pyrimidine or pyridine useful in the prevention and/or […]