Non-invasive diagnosis of steatohepatitis based on cytokeratin 18 in

The invention relates to the field of diagnosing steatohepatitis, in particular alcoholic steatohepatitis. By following studies on a cohort of nearly […]

Use of albumin isoforms profiles for the characterization of the

The inventors hypothesized that each type of liver injury can be revealed by a specific profile of HSA posttranslational modifications. Therefore, the […]

Use of let-7b or mir-21 inhibitors for the treatment inflammatory

Inflammatory bowel diseases (IBD) etiology is multifactorial. Luminal microRNAs (miRNAs) have been suspected to play a role in the promotion of […]

Diagnosis, prognosis and treatment of a disease related to a decrease

The invention relates to a method comprising a step of determining the number, concentration and/or proportion of T lymphocytes with a CD4+ CD8ααlow […]

Use of branched chain fatty acids (bcfas) for thetreatment of

The gut microbiota produces a wide variety of metabolites, which interact with intestinal cells by modulating either gene transcription or […]

Lymphotoxin alpha regulates the immunosuppressive functions of

The present invention relates to regulatory T cell and uses thereof. By their immunosuppressive and anti-inflammatory activities, regulatory T cells […]

Anti-ptf1a antibodies

Two rabbits (A and B) were immunized with a mix of two synthetic peptides of murine PTF1a sequence (one N-term peptide, KSFDNIENEPPFEFVS (aa 309-324) […]

Methods of treatment of inflammatory bowel diseases

Inventor’s general objective was to investigate the potential role of mucosal thrombin in intestinal inflammation and its mechanisms of action. […]

Bile salts bactosensor and use thereof for diagnostic and therapeutic

Bile salts are steroid acids derived from cholesterol in the liver, are released into the gastrointestinal tract to aid in digestion and are […]

Use of agents capable of inducing lc3-associated phagocytosis for

Sustained hepatic and systemic inflammation, in particular originating from monocyte/macrophages, is a driving force for chronic liver disease […]