The present invention relates to the identification of the glycogen synthase kinase-3 beta (GSK3B or GSK-3P) as a therapeutic target of pigmentation […]
Netherton syndrome (NS) is a rare recessive skin disorder caused by loss-of-function mutations in SPINK5 encoding the protease inhibitor LEKTI. NS […]
The present invention relates to a method for treating skin afflictions in a subject comprising a step of administering said subject with a […]
In the present invention, inventors investigate the representation of T cell subsets in Toxic epidermal necrolysis (TEN) a life-threatening cutaneous […]
Microvascular dysfunction remains a major contributor to the development of skin complications. The inventors assessed the impact of the local […]
Kallikrein proteolytic cascade plays a crucial role in various skin diseases. A series of coumarinic derivatives were identified with IC50 in the […]
The present invention relates to a method for promoting wound healing in a subject suffering from Ectodermal dysplasia in need thereof comprising a […]
An increasing body of evidence suggests that Nav1.7 encoded by SCN9A gene may play a key role in various pain states, including acute, inflammatory […]
The present invention relates to a method for treating vitiligo in a subject in need thereof comprising a step of administering to said subject a […]