Antibody for the treatment of myocardial infarction

The present invention relates to a method for treating MI or AMI in a subject in need thereof comprising a step of administering to said subject a […]

Apoa2 humanized transgenic mouse – line lambda

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Apoa2 humanized transgenic mouse – line beta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Apoa2 humanized transgenic mouse – line delta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Dba/1-abca1tm1jdm/j mice

The mutant ABC1 allele was generated by homologous recombination, by using a targeting vector containing a neomycin resistance and herpes simplex […]

Screening and characterization of new histone deacetylase inhibitors

Using BRET technology, we designed a method to measure histone acetylation in living cells. Cells are transfected with a vector coding for a […]

Methods of treating heart failure

Worldwide, 1% to 2% of the general adult population have heart failure (HF), which is accompanied by reduced quality of life, high morbidity, […]

Methods and pharmaceutical compositions for cardiac regeneration

The adult mammalian heart regeneration is largely prevented by the limited proliferative capacity of the resident cardiomyocytes (CMs). Here, the […]

Methods and pharmaceutical compositions for the treatment of

The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. In particular, the […]

Apelin analogs for the treatment of heart failure

The invention related to metabolically stable Apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin […]