A b cell depleting agent for the treatment of atherosclerosis or post

New anti-atherogenic strategies based on B cell modulation, and suggest that patients currently treated with CD20 antibodies for other immune-mediated […]

Antibody for the treatment of myocardial infarction

The present invention relates to a method for treating MI or AMI in a subject in need thereof comprising a step of administering to said subject a […]

Apoa2 humanized transgenic mouse – line lambda

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Apoa2 humanized transgenic mouse – line beta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Apoa2 humanized transgenic mouse – line delta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Dba/1-abca1tm1jdm/j mice

The mutant ABC1 allele was generated by homologous recombination, by using a targeting vector containing a neomycin resistance and herpes simplex […]

Screening and characterization of new histone deacetylase inhibitors

Using BRET technology, we designed a method to measure histone acetylation in living cells. Cells are transfected with a vector coding for a […]

Methods of treating heart failure

Worldwide, 1% to 2% of the general adult population have heart failure (HF), which is accompanied by reduced quality of life, high morbidity, […]

Methods and pharmaceutical compositions for cardiac regeneration

The adult mammalian heart regeneration is largely prevented by the limited proliferative capacity of the resident cardiomyocytes (CMs). Here, the […]

Methods and pharmaceutical compositions for the treatment of

The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. In particular, the […]