Biallelic gene mutations for the diagnosis of neonatal systemic

The present invention relates to a method and kit for identifying a subject having or at risk of having or developing an isolated neonatal systemic […]

A gene signature for diagnosing stimulator of interferon genes

Gain-of-function mutations in STING1, that codes for the Stimulator of Interferon Gene (STING), result in a severe autoinflammatory disease termed […]

Methods for prognosis and monitoring pulmonaryhypertension

In the present invention, in Pulmonary Arterial Hypertension (PAH) patient/u2019s blood samples (EFFORT cohort), inventors results indicate that […]

Methods of diagnosing acute circulatory failure

Circulatory failure generates hypoxia and leads to accumulation of reductive species in tissue and circulatory failure monitoring tools are needed but […]

Methods for predicting and preventing postoperative complications

Cardiopulmonary by-pass (CBP) during cardiac surgery leads to deleterious systemic inflammatory response. In a prospective cohort of 46 patients older […]

Use of b cell depleting agents for the treatment of rheumatic heart

Rheumatic heart disease (RHD) ranks as one of the most serious cardiovascular scourges of the past century and remains a force to be reckoned with in […]

Methods for improving relaxation of striated myocytes

The Inventors developed conditions allowing to efficiently detect differences in cardiomyocytes relaxation phases associated with increased […]

Use of inhibitors of phosphatase activity of soluble epoxide for the

The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by potentiating and/or exacerbating hypertension, […]

Nanoparticles for treating or preventing a cardiomyopathy and

Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in many chemotherapy protocols. However, their clinical […]

Gdf3 as biomarker and biotarget in post-ischemic cardiac remodeling

Markers of an intense scarring process in the early phase post- myocardial infarction (MI) are still undetermined, and the identification of patients […]