Methods of prognosis and treatment of patients suffering from cancer

Lung fibroblast play an important role in lung cancer tumor microenvironment (TME). Senescence is involved in the pathophysiology of tumorogenesis. […]

New prognostic method of kidney failure

The present invention relates to the prediction of kidney injury. In this study, the inventors studied the transcriptomic landscape in AAV-GN to find […]

Stratificate and method to treat a patient suffering from a cancer

The present invention relates the stratification and treatment of patient suffering from a cancer. In this study, the inventors analyzed the adenosine […]

Biallelic gene mutations for the diagnosis of neonatal systemic

The present invention relates to a method and kit for identifying a subject having or at risk of having or developing an isolated neonatal systemic […]

A gene signature for diagnosing stimulator of interferon genes

Gain-of-function mutations in STING1, that codes for the Stimulator of Interferon Gene (STING), result in a severe autoinflammatory disease termed […]

The circular rna circltbp2 as a biomarker and biotarget in

Intrahepatic cholangiocarcinoma (iCCA) is a deadly cancer worldwide with an increasing incidence and limited therapeutic options. Therefore, there is […]

Vasorin as a biomarker and biotarget in nephrology

Aiming to identify factors underlying podocytes loss, the inventors revealed a markedly decreased expression of Vasorin (VASN) using comparative deep […]

Methods and compositions for treating triple negative breast cancer

Inventors analyzed the prognostic value of tumor and stromal-derived SPARC in a large series that included 148 non-metastatic TNBC patients with a […]

Method for diagnosing colorectal cancer

The present invention relates to the diagnosing of colorectal cancer. The inventors have thus designed an efficient, rapid and cost-effective method […]

Methods and compositions for treating cell senescence accumulation

The inventors have surprisingly demonstrated that GD3 positive senescent cells inhibit NK cell in vitro and in vivo while GD3 negative senescent cells […]