Methods and compositions for modulating macrophages polarization

Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte differentiation compared to q-VD-OH by its ability to […]

Methods of treatment of inflammatory bowel diseases

Inventor’s general objective was to investigate the potential role of mucosal thrombin in intestinal inflammation and its mechanisms of action. […]

Use of inhibitors of phosphatase activity of soluble epoxide for the

The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by potentiating and/or exacerbating hypertension, […]

Nanoparticles for treating or preventing a cardiomyopathy and

Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in many chemotherapy protocols. However, their clinical […]

Antigenic peptides deriving from urocortin 3 and uses thereof for the

Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?- cell destruction in type 1 diabetes (T1D), none of their target […]

Antigenic peptides deriving from pcsk2 and uses thereof for the

Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?-cell destruction in type 1 diabetes (T1D), none of their target […]

Antigenic peptides deriving from secretogranin v and uses thereof for

Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?- cell destruction in type 1 diabetes (T1D), none of their target […]

Use of agents capable of inducing lc3-associated phagocytosis for

Sustained hepatic and systemic inflammation, in particular originating from monocyte/macrophages, is a driving force for chronic liver disease […]

Gdf3 as biomarker and biotarget in post-ischemic cardiac remodeling

Markers of an intense scarring process in the early phase post- myocardial infarction (MI) are still undetermined, and the identification of patients […]

Use of retinoic acid receptor (rar) agonists forreversin g,

Aortic valve calcification is a condition in which calcium deposits form on the aortic valve in the heart. These deposits can cause narrowing at the […]