Hepcidin antagonists for use in the treatment of inflammation

The present invention relates to a hepcidin antagonist for use in the treatment of inflammatory diseases. TLR4-dependant intestinal hepcidin induces […]

Diagnosis, prognosis and treatment of a disease related to a decrease

The invention relates to a method comprising a step of determining the number, concentration and/or proportion of T lymphocytes with a CD4+ CD8ααlow […]

New vaccinal strategy to prevent or treat rheumatoid arthritis

The present invention relates to field of treatment of rheumatoid arthritis. The inventors propose that PAD4, one of the enzymes which convert […]

Methods and pharmaceutical compositions for the treatment of systemic

The present invention relates to methods and pharmaceutical compositions for the treatment of systemic mastocytosis. The inventors showed the effect […]

Use of tcr-deficient car-tregs in combination with anti-tcr complex

The present invention is defined by the claims. In particular, the present invention relates to the use of TCR-deficient CAR-Tregs in combination with […]

A cxcr3b antagonist for the treatment of vitiligo

The present invention relates to a method for treating vitiligo in a subject in need thereof comprising a step of administering to said subject a […]

Mutated strain for the development of attenuated vaccine against zika

The present invention relates to a genomic sequences encoding for an attenuated mutant Zika virus. The inventors have introduced some specific […]

Rankl to boost thymic regeneration

Cytoablative treatments lead to severe damages on thymic epithelial cells (TECs), which result in delayed de novo thymopoïesis and a prolonged period […]