Using NLRP3-deficient U937 cells reconstituted with doxycycline-inducible NLRP3 variants in response to NLRP3 induction, the present inventors have […]

Alzheimer/u2019s disease is strongly linked to biological aging and bioenergetic abnormalities. Systemic dysregulation of metabolism is a hallmark of […]

Systemic lupus erythematosus (SLE) is an autoimmune disease in which circulating immune complexes can cause different types of glomerulonephritis, […]

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of CD1a by Sézary cells. CD1a therefore […]

The present invention relates the stratification and treatment of patient suffering from a cancer. In this study, the inventors analyzed the adenosine […]

The present invention relates to a method and kit for identifying a subject having or at risk of having or developing an isolated neonatal systemic […]

Gain-of-function mutations in STING1, that codes for the Stimulator of Interferon Gene (STING), result in a severe autoinflammatory disease termed […]

Aiming to identify factors underlying podocytes loss, the inventors revealed a markedly decreased expression of Vasorin (VASN) using comparative deep […]

In the present invention, in Pulmonary Arterial Hypertension (PAH) patient/u2019s blood samples (EFFORT cohort), inventors results indicate that […]

CD4+ Foxp3- conventional T cells (Tconv) play a key role in the inflammatory process involved in rheumatoid arthritis (RA). It is now becoming […]