Novel melanoma antigen peptide and uses thereof

The invention relates to peptides derived from the MELOE antigen for therapeutic vaccination against cancer. A phase I clinical trial for ex-vivo […]

Methods and compositions for treating pulmonary alveolar proteinosis

The present invention relates to a method for treating pulmonary alveolar proteinosis related to MARS gene mutations in a subject in need thereof […]

Use of il-6 inhibitors for the treatment of acute chest syndrome in

Acute chest syndrome (ACS) is a common and potentially lethal form of acute lung injury in sickle cell disease (SCD). Because pathophysiology remains […]

Methods and pharmaceutical compositions for the treatment of acute

An easily administrable drug treatment to increase the recanalization rate associated with intravenously t-Pa would represent a major advance in the […]

Methods and compositions for promoting wound healing in a subject

The present invention relates to a method for promoting wound healing in a subject suffering from Ectodermal dysplasia in need thereof comprising a […]

Novel melanoma antigens

The invention relates to melanoma antigen named MELOE and their use for preventing, treating and diagnosing melanoma. […]

A b cell depleting agent for the treatment of atherosclerosis or post

New anti-atherogenic strategies based on B cell modulation, and suggest that patients currently treated with CD20 antibodies for other immune-mediated […]

Apelin for the treatment of type 2 diabetes

Use of Apelin in humans has a positive effect on insulin sensitivity with a good tolerance and a good safety. Thus, a first object of the invention […]