Method for modulating the differentiation and functions of human

Type 1 conventional dendritic cells (cDC1s) and plasmacytoid dendritic cells (pDCs) are thought to be critical for anti-tumor or antiviral immunity. […]

Modulating the expression and/or activity of gas7 for modulating viral

Macrophages (MØ) are critical for the detection and clearance of pathogens and yet also serve as replication niches for multiple infectious agents. […]

Alphavirus nsp3 helical tubular scaffolds

Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current […]

Methods for the treatment of th2-mediated diseases

Voltage-dependent calcium channels (Cav1) contribute to T-cell activation. The inventors previously showed that Th2 cells co-express Cav1.2 and Cav1.3 […]

Methods for the diagnosis, treatment and analysis ofnlrp3-associated

NLRP3-associated autoinflammatory disease is a heterogenous group of monogenic conditions caused by NLRP3 gain-of-function mutations. The poor […]

Use of branched chain fatty acids (bcfas) for thetreatment of

The gut microbiota produces a wide variety of metabolites, which interact with intestinal cells by modulating either gene transcription or […]

Non-invasive imaging of tumor pd-l1 expression using radiolabeled

The present invention relates to a method for identifying patients sufferingfrom or suspected to suffer from a cancer involving a solid tumor […]