Modulating the expression and/or activity of gas7 for modulating viral

Macrophages (MØ) are critical for the detection and clearance of pathogens and yet also serve as replication niches for multiple infectious agents. […]

Alphavirus nsp3 helical tubular scaffolds

Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current […]

New method to treat infectious diseases

The present invention relates to the treatment of infectious diseases. In this study, the inventors identified the potential protective mechanisms […]

Methods for the treatment of endometriosis

Endometriosis is a chronic oestrogen-dependent inflammatory disease characterised by the presence of endometrial tissue outside the uterine cavity. […]

Methods of treating iron deficiency-related diseases

Anemia, defined as a decreased quantity of circulating functional red blood cells, is a major source of morbidity and mortality affecting a-third of […]

Methods of treatment of iron overload associated diseases

In the present invention, inventor identified the hepatokine FGL1 as a previously undescribed suppressor of hepcidin that is highly induced in the […]

Methods of treatment of metabolic disorders

In the present invention SLC5A9 gene (encoding SGLT4 protein) regulation was analyzed in the intestine of patients before and after weight-loss […]

Hepcidin antagonists for use in the treatment of inflammation

The present invention relates to a hepcidin antagonist for use in the treatment of inflammatory diseases. TLR4-dependant intestinal hepcidin induces […]

Methods for the treatment of th2-mediated diseases

Voltage-dependent calcium channels (Cav1) contribute to T-cell activation. The inventors previously showed that Th2 cells co-express Cav1.2 and Cav1.3 […]

Methods for the treatment of food allergy

The incidence of food allergy has dramatically increased over the last three decades in industrialized countries, now affecting more than 200 million […]