Modified escherichia coli strain nissle and treatment of

The invention relates to the field of modified Escherichia coli strain Nissle 1917 (EcN) and its use for treating gastro-intestinal disorders. The […]

Antisense oligonucleotides and ceftriaxone in the strategy against

The present invention relates to the treatment of infections due to antibiotic-resistant bacteria. Antimicrobial resistance (AMR) has been observed at […]

Use of drugs that stiffen mature gametocytes for blocking transmission

The spleen clears rigid erythrocytes from the circulation. Drug-induced stiffening of Plasmodium falciparum intra-erythrocytic sexual stages (mature […]

New clofoctol formulation

The invention concerns a new galenic formulation of CFT (clofoctol) allowing the administration of this antibiotic in aerosol form with the objective […]

Targeted-antibacterial-plasmids combining conjugation andcrispr /cas

The global emergence of drug-resistant bacteria leads to the loss of efficacy of our antibiotics arsenal and severely limits the success of currently […]

Aerosol composition for pulmonary delivery of flagellin

The present invention arises from a formulation study in order to define the best excipients including buffer, surfactant, sugar and amino acid to […]

Gram-negative bacteria efflux pump inhibitors

Antimicrobial resistance is a global problem, rendering conventional treatments less effective and requiring innovative strategies to combat this […]

Method for modulating the differentiation and functions of human

Type 1 conventional dendritic cells (cDC1s) and plasmacytoid dendritic cells (pDCs) are thought to be critical for anti-tumor or antiviral immunity. […]

Modulating the expression and/or activity of gas7 for modulating viral

Macrophages (MØ) are critical for the detection and clearance of pathogens and yet also serve as replication niches for multiple infectious agents. […]

Alphavirus nsp3 helical tubular scaffolds

Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current […]