Methods and pharmaceutical compositions for enhancing cd8+t

Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer patients by unleashing exhausted CD8+ T-cell […]

Inhibitor of the heterochromatin protein 1 (hp1) for modulating th

The present invention relates to a treatment of Th cell-associated disorders. Here, theinventors The inventors show that Treg-dependent suppressive […]

Methods for the diagnosis and treatment of acute lymphoblastic

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in need thereof comprising administering to the […]

Anti-neurotensin long fragment and anti-neuromedin n long fragment

The present invention relates to an antibody, which is capable of binding to theNeuromedin N long fragment, and Neurotensin long fragment with high […]

A composition comprising lipid nanoparticles and an antifungal polyene

The present invention relates to a composition comprising an aqueous phase, a polyene antifungal and lipid nanoparticles which are dispersed in the […]

Modified escherichia coli strain nissle and treatment of

The invention relates to the field of modified Escherichia coli strain Nissle 1917 (EcN) and its use for treating gastro-intestinal disorders. The […]

Antisense oligonucleotides and ceftriaxone in the strategy against

The present invention relates to the treatment of infections due to antibiotic-resistant bacteria. Antimicrobial resistance (AMR) has been observed at […]

Use of drugs that stiffen mature gametocytes for blocking transmission

The spleen clears rigid erythrocytes from the circulation. Drug-induced stiffening of Plasmodium falciparum intra-erythrocytic sexual stages (mature […]

New 6-6 or 5-6 fused bicyclic compounds comprisingpyrimidine useful in

The present invention relates to new specific 6-6 or 5-6 fused bicyclic compounds comprising pyrimidine or pyridine useful in the prevention and/or […]

New clofoctol formulation

The invention concerns a new galenic formulation of CFT (clofoctol) allowing the administration of this antibiotic in aerosol form with the objective […]