Hepcidin antagonists for use in the treatment of inflammation

The present invention relates to a hepcidin antagonist for use in the treatment of inflammatory diseases. TLR4-dependant intestinal hepcidin induces […]

Methods for the treatment of th2-mediated diseases

Voltage-dependent calcium channels (Cav1) contribute to T-cell activation. The inventors previously showed that Th2 cells co-express Cav1.2 and Cav1.3 […]

Methods for the treatment of food allergy

The incidence of food allergy has dramatically increased over the last three decades in industrialized countries, now affecting more than 200 million […]

Methods and compositions for reparing airway epithelial cell in

The present invention relates to the treatment of fibrosis cystic. The inventors have demonstrated that specialised pro-resolution lipid mediators […]

Use of let-7b or mir-21 inhibitors for the treatment inflammatory

Inflammatory bowel diseases (IBD) etiology is multifactorial. Luminal microRNAs (miRNAs) have been suspected to play a role in the promotion of […]

Methods for the diagnosis, treatment and analysis ofnlrp3-associated

NLRP3-associated autoinflammatory disease is a heterogenous group of monogenic conditions caused by NLRP3 gain-of-function mutations. The poor […]

Gsk3b and uses thereof in the diagnostic and treatment of

The present invention relates to the identification of the glycogen synthase kinase-3 beta (GSK3B or GSK-3P) as a therapeutic target of pigmentation […]

Diagnosis, prognosis and treatment of a disease related to a decrease

The invention relates to a method comprising a step of determining the number, concentration and/or proportion of T lymphocytes with a CD4+ CD8ααlow […]

New vaccinal strategy to prevent or treat rheumatoid arthritis

The present invention relates to field of treatment of rheumatoid arthritis. The inventors propose that PAD4, one of the enzymes which convert […]

Use of branched chain fatty acids (bcfas) for thetreatment of

The gut microbiota produces a wide variety of metabolites, which interact with intestinal cells by modulating either gene transcription or […]