Back to results

Allele-specific silencing therapy for dynamin 2-related diseases

The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.

More information (PDF)

Keywords: Centronuclear Myopathies -

Patent Application number: European Procedure (Patents) (EPA) - 29 Nov. 2016 - 16306575.8

Inventors:

BITOUN Marc,PRUDHON Bernard,TROCHET Delphine

Publications:

EMBO Mol Med. 2018 Feb;10(2):239-253. doi: 10.15252/emmm.201707988.

Reference:

BIO17148-T1

Inserm Transfert
Business Developer

Phone

E-mail

Patent filling date: 29-11-2016

Rare disease: Yes

Second indication: No

You might also be interested in

RT00624

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Ualh cell line

UALH were generated by transfection of osteocarcinoma cancer U2OS cells with the […]

Read more

RT00586

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Ualh har cell line

UALH were generated by transfection of osteocarcinoma cancer U2OS cells with the […]

Read more

RT00582

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Palm cell line

PALM were generated by co-transfection of cervical cancer PC3 cells with the […]

Read more

RT00583

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Meln (her alpha) cell line

MELN were generated by transfection of breasr cancer MCF-7 cells with the […]

Read more

RT00623

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Hrln (hrar alpha) cell line

HRLN were generated by transfection of cervical cancer HeLa cells with the […]

Read more

RT00626

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Ug5ln gal4-hmr cell line

UG5LN were generated by transfection of osteocarcinoma cancer U2OS cells with the […]

Read more

RT00625

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Ug5ln cell line

UG5LN were generated by transfection of osteocarcinoma cancer U20S cells with the […]

Read more

RT00558

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Hg5ln gal4-hppar alpha cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

Read more

RT00559

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Hg5ln gal4-hppar gamma cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

Read more

RT00569

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Hg5ln gal4-hppar beta/delta cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

Read more

RT00585

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Hg5ln rtr alpha cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

Read more

RT00588

Industry Research (screening, tox.studies, bioreactor, ...) Uses:

Oncology Therapy Area:

Cell Lines Type of research tool:

Hg5ln hpxr cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

Read more