147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

Our Technology Offers

Welcome to our Technology Offers website

You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

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BIO22284-D1

Use of the population of slamf4+ ccr5+ effector memory cd4+ t cells as

CD4+ Foxp3- conventional T cells (Tconv) play a key role in the inflammatory process involved in rheumatoid arthritis (RA). It is now becoming […]

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BIO21469-T1

Use of irap inhibitors for the treatment of inflammatory diseases

Upon activation, mast cells rapidly release preformed inflammatory mediators from large cytoplasmic granules via regulated exocytosis. This acute […]

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BIO19058-T1

New vaccinal strategy to prevent or treat rheumatoid arthritis

The present invention relates to field of treatment of rheumatoid arthritis. The inventors propose that PAD4, one of the enzymes which convert […]

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BIO21443-D1

Method for diagnosing collagen degradatation associated disease

The Inventors have developed an ELISA of a new molecular marker detecting a neoepitope generated from the cleavage of the α1 chain of type III […]

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BIO12348-D1

A 7 protein signature for stratifying patients with rheumatoid

Rheumatoid arthritis (RA) is a chronic, auto-immune and inflammatory polyarthritis which induces joint damage and disability. Thanks to the better […]

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BIO12129-T1

Il15 antagonist to treat inflammation

The present relates to interleukin 15 (IL-15) antagonists and uses thereof, in particular for the treatment of autoimmune diseases and inflammatory […]

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BIO23509-T1

Methods of treating familial adenomatous polyposis

Familial adenomatous polyposis (FAP) patients harbor mutations in the APC gene and will develop […]

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BIO21512-T1

Engraftment of engineered mesenchymal stromal

Dendritic cells (DCs) control the activation and infiltration of CD8+ T cells within the tumor […]

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BIO24003-T1

Composition comprising furin-inhibited car

CAR macrophages (CAR-M) can phagocyte tumor cells expressing a target antigen. It is herein shown […]

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BIO1634102-T1

Methods and pharmaceutical compositions for

Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer […]

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BIO22194-T1

Inhibitor of the heterochromatin protein 1 (hp1)

The present invention relates to a treatment of Th cell-associated disorders. Here, the
inventors […]

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BIO20377-T1

Methods and pharmaceutical compositions for

Tumour-specific molecular targets and alternative therapeutic strategies for triplenegative breast […]

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BIO17187-T1

Method for treating cancer

The present invention relates to a method of treating HER2/
EU overexpressing cancers. The […]

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BIO23521-T1

Methods of treating cancer combining uros

Thanks to its very high genome-editing efficiency, CRISPR-Cas9 technology could be a promising […]

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BIO22282-T1

Garp as a biomarker and biotarget in t-cell

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the […]

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BIO2114501-T1

Methods for the diagnosis and treatment of t

T-cell malignancies are a broad, heterogenous group of diseases and include T-cell lymphomas and […]

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BIO24047-T1

Methods and pharmaceutical composition for

Inventors demonstrated that an epigenetic regulator CBX3 antagonizes IFNγ signalling via directly […]

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BIO22280-T1

Methods for the diagnosis and treatment of acute

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in […]

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