147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

Our Technology Offers

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You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

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Methods and pharmaceutical compositions for enhancing cd8+t

Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer patients by unleashing exhausted CD8+ T-cell […]

Slitrk6 as a target for cancers associated with activation of the mapk

The response of subjects suffering from cancer to MAPK inhibitors is dramatically impaired by secondary resistances and rapid relapse. So far, the […]

Method for discriminating mono-immunotherapy from combined

Combination therapy with anti-PD-1 and anti-CTLA-4 is now indicated in many cancers. It appears to be more effective than anti-PD-1 monotherapy, but […]

Methods and compositions for predicting and treating uveal melanoma

Here, in multi-scale analyses using single-cell RNA sequencing of six different primary uveal melanomas, inventors uncover a previously unrecognized […]

Methods and compositions for predicting and treating uveal melanoma

Here, in multi-scale analyses using single-cell RNA sequencing of six different primary uveal melanomas, inventors uncover a previously unrecognized […]

Methods and compositions for treating melanoma

The present invention relates to a method and composition for treating melanoma. More particularly, inventors have shown that high expression of USP14 […]

Stratification of melanoma patients for immune checkpoint inhibitor

Immune checkpoint inhibitors (ICI) have revolutionized therapy for advanced cancer, however many patients still do not respond to treatment. However, […]

New biomarker for prognosis and treatment of patients with melanoma

The present invention relates to a method and composition for treating melanoma, aggressive/invasive melanoma, metastatic melanoma or melanoma […]

Novel b-raf inhibitors devoid of rapid metabolism and of binding to

The present invention relates to N-(3-(5-(pyrimidin-4-yl)thiazol-4-yl)phenylsulfonamide compounds which are useful as inhibitors of protein kinases, […]

Sphingosine kinase 1 a new tumor target for enhancing the potency of

The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates […]

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