Search Results – Inserm Transfert

Our Technology Offers

Welcome to our Technology Offers website

You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

CHIM18040-T1

Drug Field of development:

Colorectal Cancer Therapy Area:

Product Type of patent:

Compounds targeting hsp110 protein for cancer treatment

HSP110 is involved in multiple tumorigenic processes, but no inhibitor was known to date. The inventors have identified for the first time HSP110 […]

CHIM1902901-T1

Drug Field of development:

Cardiomyopathy Therapy Area:

Method Type of patent:

Nanoparticles for treating or preventing a cardiomyopathy and

Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in many chemotherapy protocols. However, their clinical […]

CHIM19384-T1

Drug Field of development:

Idiopathic pulmonary fibrosis Therapy Area:

Method Type of patent:

Selective pharmacological inhibition of epac1 for the treatment of

The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no cure for IPF. The inventors showed that EPAC1 […]

BIO20193-T1

Drug Field of development:

Diabetic nephropathy Therapy Area:

Method Type of patent:

Methods and pharmaceutical compositions for the treatment of chronic

The present invention relates to methods and pharmaceutical compositions for the treatment of chronic kidney disease. The inventors used the CMap […]

BIO19407-T1

Drug Field of development:

Idiopathic pulmonary fibrosis Therapy Area:

Method Type of patent:

Methods and compositions for modulating macrophages polarization

Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte differentiation compared to q-VD-OH by its ability to […]

BIO19459-T1

Drug Field of development:

Chronic Heart Failure Therapy Area:

Method Type of patent:

Use of mast cell stabilizer for the treatment of heart failure with

Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a growing epidemiologic problem. However, the […]

BIO19153-T1

Drug Field of development:

Thalassemia Therapy Area:

Product Type of patent:

Correction of beta-thalassemia phenotype by genetically engineered

The present invention relates to a genetically modified hematopoietic stem cell (HSC) comprising, in at least one α-globin gene comprised in the […]

BIO18299-T1

Drug Field of development:

Cardiovascular Diseases Therapy Area:

Target Type of patent:

Use of inhibitors of phosphatase activity of soluble epoxide for the

The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by potentiating and/or exacerbating hypertension, […]

BIO18162-T1

Drug Field of development:

Vascular dysfunction Therapy Area:

Target Type of patent:

Use of pi3kc2¿ inhibitors for the preservation of vascular

Ischemic conditions are a leading cause of death for both men and women. Ischemia, a condition characterized by reduced blood flow and oxygen to an […]

BIO18120-T1

Drug Field of development:

Melanoma Therapy Area:

Target Type of patent:

Sphingosine kinase 2 inhibitors in combination with immune checkpoint

Immune checkpoint blockade therapy is based on the inhibition of the tumor-mediated suppression of anticancer immune responses. However, the efficacy […]

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Our Technology Offers

Compounds targeting hsp110 protein for cancer treatment

Nanoparticles for treating or preventing a cardiomyopathy and

Selective pharmacological inhibition of epac1 for the treatment of

Methods and pharmaceutical compositions for the treatment of chronic

Methods and compositions for modulating macrophages polarization

Use of mast cell stabilizer for the treatment of heart failure with

Correction of beta-thalassemia phenotype by genetically engineered

Use of inhibitors of phosphatase activity of soluble epoxide for the

Use of pi3kc2¿ inhibitors for the preservation of vascular

Sphingosine kinase 2 inhibitors in combination with immune checkpoint

You might also be interested in

Nanoparticles for treating or preventing a

Compounds targeting hsp110 protein for cancer

Selective pharmacological inhibition of epac1 for

Methods and pharmaceutical compositions for the

Use of mast cell stabilizer for the treatment of

Methods and compositions for modulating

Correction of beta-thalassemia phenotype by

Use of inhibitors of phosphatase activity of

Use of pi3kc2¿ inhibitors for the preservation of

Sphingosine kinase 2 inhibitors in combination

Use of shp2 inhibitors for the treatment of

Methods and compositions for treating liver

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Inserm Transfert