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Novel target candidate for the prevention and treatment of respiratory infections / COPD-AE

The present invention relates to methods and pharmaceutical compositions for the prevention and treatment of respiratory bacterial infections and more particularly of superinfection and acute exacerbation of chronic obstructive pulmonary disease with a therapeutically effective amount of an antagonist of IL-20 cytokines. Proof of concept has been achieved in mouse models with a mAb targeting IL20R

Keywords : Infectious diseases, Respiratory, IL-20, COPD acute exacerbation, antibacterials
Patent Application number : EP14306868.2
Patent Application date : 2014-11-24
Multidisciplinary field : -
Technology/Engineering : -
Technological Platform : -
Rare disease : -
Second indication : -
Inventors : Magdiel PEREZ-CRUZ
Bachirou KONE
Philippe GOSSET
Publications : -

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