Real time no measurement

Real time constant amperometric detection of NO in tissues/cells.

This gaseous neurotransmitter has a very short half-life (*5 s) and is usually studied by using indirect detection.
We set up an original method to measure in real-time conditions hypothalamic nitric oxide production after intragastric glucose administration.

Keywords: NO , ROS
Scientist's name: Philippe VALET
Claude KNAUF
Publications:
T. DUPARC D. NASLAIN A. COLOM G.G. MUCCIOLI N. MASSALY N.M. DELZENNE P. VALET P.D. CANI C. KNAUF. Jejunum inflammation in obese and diabetic mice impairs enteric glucose detection and modifies nitric oxide release in the hypothalamus. Antiox. Red. Signal. 14: 415-23 2011.

T. DUPARC
A. COLOM P.D. CANI N. MASSALY S. RASTRELLI A. DROUGARD S. LE GONIDEC L. MOULÉDOUS B. FRANCES I. LECLERCQ C. LLORENS-CORTES J.A. POSPISILIK N.M. DELZENNE P. VALET I. CASTAN-LAURELL & C. KNAUF. Central apelin controls glucose homeostasis via a nitric oxide dependent pathway in mice. Antiox. Red. Signal. 2011.

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