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therapeuticpublished patents
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Immune checkpoint blockade therapy is based on the inhibition of the tumor-mediated suppression of anticancer immune responses. However, the efficacy […]
Inflammation is a prominent feature of ischemia-reperfusion injury (IRI) characterized by leukocyte infiltration and renal tubular injury. However, […]
The response of subjects suffering from cancer to MAPK inhibitors is dramatically impaired by secondary resistances and rapid relapse. So far, the […]
The present invention relates to methods of enhancing the potency of incretin-based drugs in subjects in need thereof. Through different animal […]
The present invention relates to methods and pharmaceutical compositions for the prevention and treatment of respiratory bacterial infections and more […]
The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates […]
The present invention relates to the diagnosis of gastrointestinal stromal tumors (GISTs). The present invention also relates to methods and […]
Ageing myocardium undergoes structural and functional changes characterized by progressive cardiomyocyte hypertrophy, interstitial fibrosis and […]
The mechanisms driving the development of extracapillary lesions in focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) […]
Obesity is associated with low-grade inflammation in adipose tissue (AT) and dysfunctional adipocytes producing inflammatory molecules. A recent study […]
The present invention relates to a method for treating a subject suffering from a cancer comprising […]
The invention is in the field of therapy of antibody deficiencies such as immune diseases and […]
The invention is in the field of therapy of gut inflammatory diseases such as Inflammatory Bowel […]
Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte […]
Inventor's general objective was to investigate the potential role of mucosal thrombin in […]
The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by […]
Aortic valve calcification is a condition in which calcium deposits form on the aortic valve in the […]
Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a […]
Obesity is associated with low-grade inflammation in adipose tissue (AT) and dysfunctional […]
Ageing myocardium undergoes structural and functional changes characterized by progressive […]
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