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Transgenic mouse model for myotonic dystrophy: dm300 carrying 300 ctg

Transgenic mouse model carrying the myotonic dystrophy type 1 (DM1) locus (45kb of human sequences) with the DMPK gene and about 300 unstable CTG […]

Methods and compositions for treating cell senescence accumulation

The inventors have surprisingly demonstrated that GD3 positive senescent cells inhibit NK cell in vitro and in vivo while GD3 negative senescent cells […]

Methods for prognosis, stratification and monitoring of the severity

In the present invention inventors used measured cytokine levels in serum of patients with COVID-19, at the time of hospital admission. Thereafter, […]

In vitro tests allowing to identify the potential for mdm2 inhibitors

TP53 mutations are the most frequent mutations in all cancer subtypes and their acquisition are key events leading to the transformation of chronic […]

New method to evaluate pancreatic prognosis

The present invention relates to the prediction of the survival time of a patient suffering of a pancreatic cancer. In this study, the inventors aimed […]

Methods for the diagnosis and treatment of t cell-lymphomas ccr8

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]

Method for diagnosing pancreatic cancer

The present invention relates to the diagnostics of pancreatic cancer. The inventors engineered a novel biomarker discovery approach, tailored for […]

Methods of determining whether a patient suffering froma

Pheochromocytomas produce and store catecholamines. The release of excessive amounts of catecholamine can lead to life-threatening […]

Method for pronosis and treating a patient suffering from cancer

Complement components form a plasma innate immune cascade but could also serve as multitasking proteins, as they have functions beyond this system. […]

Bile salts bactosensor and use thereof for diagnostic and therapeutic

Bile salts are steroid acids derived from cholesterol in the liver, are released into the gastrointestinal tract to aid in digestion and are […]

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