3d cell omics – clinical proteomics platform

For your Clinical investigations, they propose to apply 3D culture cell methods to further your knowledge of disease, pathways, targets and drugs effects.

3D Cell Omics offers :
- Technology that mimics the tumor microenvironment
- Study of drug effects on different cell line,
- Drug following by mass spectrometry imaging,
- Biomarkers hunting,
- Large scale proteins identification and relative quantification.

3D Cell Omics will assist you throughout all steps of your project from culture of your cell lines to the data analysis.

- Maintenance of cell lines
- Access to innovative technologies : creation of mixed spheroid, invasion computation software, 3D organs Bioprinting, exosome isolation and count …
- Data processing and statistical analysis for identifications and relative quantification of markers.


For more information : http:/www.laboratoire-prism.fr/index.php/platforms/3d-cellomics

Interest / Relevance: - Large index of cell lines (30 different cell line from different species).
- Mixed spheroid creation : association of cancer cells AND immune cells in 3D culture for mimic tissue microenvironnement.
- Large scale of different test : invasion test, viability test, MS/MS, imaging, fluorescence.
- 3D organs bioprinting.
- Exosome isolation and count with Nanosight.
- Isolated organs, biopsies, tissue sections, isolated cells layer, 2D or 3D cell culture, cell secretomes and body fluids (plasma, CSF) .
- Combined Multi-Omics analysis (metabolomics, lipidomics and proteomics).
- Design, execution and analysis of experiments.
- Get closer to the tumor microenvironment for testing drugs.

Up-to-date software for data analysis, proteins identification, label free quantification and invasion area quantification.
Members of 3D Cell Omics platform lead research efforts in proteomics area to apply these cutting-edge methods to answer your question.
Scientist's name: Michel SALZET
Publications:
1). ChemPhysChem. 2018 doi: 10.1002/cphc.201701198

2). MCP. 2018
doi: 10.1074/mcp.RA117.000443

3). Sci Rep. 2016
doi: 10.1038/srep19360

4). MCP. 2015
doi: 10.1074/mcp.M115.052480

Reference:

RT00507

Business Developper
contact
Inserm Transfert
Research Tools
Accessible for: Fee-for-service research, Collaboration, Training / Know-How License
Equipment available: Exosome counter, Nanosight, 3D organoid bioprinter, biobots, Ventana histological robot...
Rare disease: No
Last update: 11/09/2024

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