Modulating the expression and/or activity of gas7 for modulating viral

Macrophages (MØ) are critical for the detection and clearance of pathogens and yet also serve as replication niches for multiple infectious agents. […]

Alphavirus nsp3 helical tubular scaffolds

Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current […]

Methods of prognosis and treatment of patients suffering from cancer

Lung fibroblast play an important role in lung cancer tumor microenvironment (TME). Senescence is involved in the pathophysiology of tumorogenesis. […]

Cd1a as a biomarker and biotarget in cutaneous t-cell lymphomas

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of CD1a by Sézary cells. CD1a therefore […]

Indole-3-propionic acid as an important contributor to viral infection

The gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, the inventors used […]

Vasorin as a biomarker and biotarget in nephrology

Aiming to identify factors underlying podocytes loss, the inventors revealed a markedly decreased expression of Vasorin (VASN) using comparative deep […]

Cd81 as a biomarker and biotarget in t-cell malignancies

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the overexpression of CD81 by Sézary cells. CD81 has also […]

Use of hif-1¿ stabilizing agents for the treatment of type i

Type I interferonopathies represent a subgroup of autoinflammatory diseases caused by mutations in genes associated with proteasome degradation or […]

Methods for the treatment of food allergy

The incidence of food allergy has dramatically increased over the last three decades in industrialized countries, now affecting more than 200 million […]

Methods and compositions for treatment of rac2 monogenic disorders

A growing number of patients presenting severe combined immunodeficiencies attributed to monoallelic RAC2 variants have been identified. The […]