Method for modulating the differentiation and functions of human

Type 1 conventional dendritic cells (cDC1s) and plasmacytoid dendritic cells (pDCs) are thought to be critical for anti-tumor or antiviral immunity. […]

New adjuvant to improve the innate immunity

The present invention relates to the field of adjuvant and vaccination. In the present study, the inventors investigate whether P1, in addition to […]

Modulating the expression and/or activity of gas7 for modulating viral

Macrophages (MØ) are critical for the detection and clearance of pathogens and yet also serve as replication niches for multiple infectious agents. […]

Alphavirus nsp3 helical tubular scaffolds

Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current […]

New method to treat infectious diseases

The present invention relates to the treatment of infectious diseases. In this study, the inventors identified the potential protective mechanisms […]

Hepcidin antagonists for use in the treatment of inflammation

The present invention relates to a hepcidin antagonist for use in the treatment of inflammatory diseases. TLR4-dependant intestinal hepcidin induces […]

Methods for the treatment of th2-mediated diseases

Voltage-dependent calcium channels (Cav1) contribute to T-cell activation. The inventors previously showed that Th2 cells co-express Cav1.2 and Cav1.3 […]

Methods for the treatment of food allergy

The incidence of food allergy has dramatically increased over the last three decades in industrialized countries, now affecting more than 200 million […]

Methods and compositions for reparing airway epithelial cell in

The present invention relates to the treatment of fibrosis cystic. The inventors have demonstrated that specialised pro-resolution lipid mediators […]

Use of let-7b or mir-21 inhibitors for the treatment inflammatory

Inflammatory bowel diseases (IBD) etiology is multifactorial. Luminal microRNAs (miRNAs) have been suspected to play a role in the promotion of […]