published patents


published patents


research tools


published patents

Our Technology Offers

Welcome to our Technology Offers website

You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

Technique to isolate live renal proximal tubular cells from any mouse

We isolate renal proximal tubular cells using the proximal tubular marker Prominin-1. We use a 4°C, enzyme free protocole allowing high quality […]

Ex vivo culture system for screening compounds targeting

A novel, ex vivo niche-based hypoxic culture system for maintaining Leukaemia Initiating Cells (LICs) from patients and an associated method to […]

Xenograft models to study stem and chemoresistant cells, and to assess

We have recently contributed to establish a robust xenotransplantation model (NSG, NRG) to study the leukemic engraftment as well as the stem cell […]

Animal models of fibrosis

UUO: This model is induced in mice or rats by unilateral ureteral ligation (UUO) of the left ureter. The animals rapidly develop, within a few days, […]

Urinary peptidome analysis

In collaboration with Mosaiques Diagnostics we can analyse biofluid proteomes for your needs using capillary electrophoresis coupled to mass […]

Screening and characterization of new histone deacetylase inhibitors

Using BRET technology, we designed a method to measure histone acetylation in living cells. Cells are transfected with a vector coding for a […]

Three-dimensional multicellular spheroid cultures

When culture in suspension many mammalian cell types can aggregate into 3D-spheroids. These multicellular cultures mimic real tissues or tumours and […]

Real time no measurement

Real time constant amperometric detection of NO in tissues/cells. This gaseous neurotransmitter has a very short half-life (*5 s) and is usually […]

Staining of human tissues for multi-color confocal microscopy analysis

This proposition describes a technique that allowed us to successfully stain human tissues with fluorochrome labelled antibodies for confocal and […]

Highly differentiated human hepatocytes in primary culture

Hepatocytes are isolated from human liver and cultured in a system that allows to maintain a highly differentiated phenotype for several weeks. In […]

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