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therapeuticpublished patents
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Welcome to our Technology Offers website You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.
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Infectious diseases
Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in many chemotherapy protocols. However, their clinical […]
The present invention relates to a method of treating disease associated with angiogenesis using an N-Methyl-D-aspartate receptor (NMDA) antagonist. […]
Markers of an intense scarring process in the early phase post- myocardial infarction (MI) are still undetermined, and the identification of patients […]
The thrombogram of FVIII-KO mice displays a prolonged time to peak and a reduced peak thrombin. The addition of the neutralizing anti-protease nexin-1 […]
Kallikrein proteolytic cascade plays a crucial role in various skin diseases. A series of coumarinic derivatives were identified with IC50 in the […]
The present invention relates to a PAK-1 and/or PAK-2 inhibitor for use in the treatment of NLRP3 inflammasome mediated IL-1beta dependent disorders […]
An increasing body of evidence suggests that Nav1.7 encoded by SCN9A gene may play a key role in various pain states, including acute, inflammatory […]
The present invention concerns an inhibitor for use for preventing and/or treating an infection with hepatitis B virus (HBV) and an in vitro screening […]
The present invention relates to method and composition for treating melanoma. The inventors have shown that a decrease in LYN expression, in melanoma […]
The present invention relates to a method for modulating blood-brain barrier (BBB) in a subject comprising a step of administering said subject with a […]
Here the inventors show, using in vivo imaging and viral approaches, that calcium released by […]
In the present invention it is shown that the inactivation of the Pyk2 gene does not alter […]
In the present invention it is shows that the inactivation of the Pyk2 gene does not alter […]
The present invention relates to a method for treating a subject suffering from a cancer comprising […]
The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no […]
HSP110 is involved in multiple tumorigenic processes, but no inhibitor was known to date. The […]
Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in […]
The present invention relates to methods and pharmaceutical compositions for the treatment of […]
Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a […]
Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte […]
The present invention relates to a genetically modified hematopoietic stem cell (HSC) comprising, […]
The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by […]
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