147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

Our Technology Offers

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You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

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Methods and compositions for treating asthma and allergic diseases

The present invention relates to allergy field. Several independent groups have recently investigated the implication of PCSK9 on inflammation and […]

Compounds targeting hsp110 protein for cancer treatment

HSP110 is involved in multiple tumorigenic processes, but no inhibitor was known to date. The inventors have identified for the first time HSP110 […]

Correction of beta-thalassemia phenotype by genetically engineered

The present invention relates to a genetically modified hematopoietic stem cell (HSC) comprising, in at least one α-globin gene comprised in the […]

Anti-cathepsin d human antibody for triple negative breast cancer

Inventors have generated two human anti-cath-D scFv fragments cloned in the human IgG1 format (F1 and E2) that efficiently bind to human and […]

Antibodies specific for il20-rb and uses thereof for the treatment of

Chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality worldwide. Acute exacerbation of COPD (AE-COPD) in […]

Methods of enhancing the potency of incretin-based drugs in subjects

The present invention relates to methods of enhancing the potency of incretin-based drugs in subjects in need thereof. Through different animal […]

Novel melanoma antigens

The invention relates to melanoma antigen named MELOE and their use for preventing, treating and diagnosing melanoma. […]

Pd-1 antibodies and pd-l1 murin antibodies

The present invention relates to PD-1 and PD-L1 antibodies to treat cancer […]

Novel b-raf inhibitors devoid of rapid metabolism and of binding to

The present invention relates to N-(3-(5-(pyrimidin-4-yl)thiazol-4-yl)phenylsulfonamide compounds which are useful as inhibitors of protein kinases, […]

Anti- protease nexin-1 conformational single domain antibodies and

The present invention relates to anti-protease nexin-1 (PN-1) conformational single domain antibodies and uses thereof in particular in the […]

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